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INVESTIGATOR'S PROFILE
 

Dr. A. MAHESH, Ph. D.,


Project Faculty
DBT- IPLS Program
School Of Biological Sciences,
Madurai Kamaraj University,
Madurai-625021,
Tamil Nadu, India.
Mobile: +91-98438 74873
E mail: mahesh.a@dbtiplsmku.org;
           mahesh.a06@gmail.com
 
Professional Experience:

  • Faculty in the School of Biological Sciences, Madurai Kamaraj University,Madurai- 625021. (Sep 2011 onwards)

 

  • Post Doctoral Scientist, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel. (July 2011- Sep 2011)
  • Post Doctoral Scientist, Department of Plant Genetics, Agricultural Research Organization, The Volcani Centre, Bet-Dagan 50250, Israel. (Jan 2009-June 2011)           

Honors and Awards

  • DST - Young Scientist- 2012
  • Konan Zoref Post- doc fellowship, Bar-Ilan University, Ramat- Gan, Israel (2011-2012)
  • University Research Fellow, Bharathidasan University, Tiruchirapalli, India (2005-2008)

Area of Interest

  • Cancer Biology
  • Drug Development and Delivery
  • Genetic Engineering.

PUBLICATIONS
Journals

  • Mahesh, A., Levy, Y., Gaba, V. and Gafni, Y. 2011. Biolistic transformation of tobacco plants using Rolling Circle Amplification (RCA) DNA product. (In preparation).
  • Mahesh, A., Levy, Y., and Gafni, Y. 2011. Production of siRNA targeted against the Ricin protein transcripts leads to inhibition of its expression in tobacco plants. (In preparation).
  • *Mahesh A, Jeyachandran R. (2013). Influence of plant growth regulators on in vitro flowering of Trichodesma indicum (Linn.) R. Br. Plant biosystems, (On line published). DOI: 10.1080/11263504.2012.727876
  • *Mahesh, A., Jeyachandran, R., Muralidhara Rao, D. and Thangadurai, D. (2012). Dose-dependent protective effect of Desmodium gangeticum (L.) DC. roots on gastric mucosal injury in experimental mice. Brazilian Journal of pharmacognosy, 22(5): 1085-1091.
  • *Sathish Climer C, Mahesh A, Sinilal B, Muralidhara Rao D, Thangadurai D. Protective effect of Indigofera aspalathoides roots on N-nitrosodiethylamine induced hepatocarcinogenesis in mice. Indian Journal of Pharmaceutical Sciences, 74 (2): 157-160.
  • *Mahesh A, Thangadurai D, Melchias G. (2011). Rapid in vitro plant regeneration from leaf explants of Launaea sarmentosa (Willd.) Schult- Bip. Biological Research, 45(2): 131-133.
  • Vimaladevi, S., Mahesh, A., Dhayanithi, N.B. and Karthikeyan, N. (2012). Mosquito larvicidal efficacy of phenolic acids of seaweed Chaetomorpha antennina (Bory) Kuetz. Biologia. (67): 212-216.
  • Mahesh, A., Thangadurai, D. and Melchias, G. (2011). Rapid in vitro plant regeneration from leaf explants of Launaea sarmentosa (Willd.) Schult- Bip. Biological Research, (Accepted).
  • Gobinath, S., Mahesh, A., Thangadurai, D. and Muralidhara Rao, D. (2011). Protective effect of Caralluma umbellate Haw. against paracetamol induced oxidative stress and hepatotoxicity in rat. Acta Biologica Hungarica. (Accepted).
  • Mahesh, A. and Jeyachandran, R. (2011). Agrobacterium rhizogenes-mediated hairy root induction in Taraxacum officinale and analysis of sesquiterpene lactones. Plant biosystems, 145: 620-626.
  • Mahesh, A., Jeyachandran, R., Cindrella, L., Thangadurai, D. and Muralidhara Rao, D. (2010). Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice. Acta Biologica Hungarica, 61(2): 175–190.
  • Mahesh, A., Shaheetha, J., Thangadurai, D. and Muralidhara Rao, D. (2009). Protective effect of Indian honey on acetaminophen induced oxidative stress and liver toxicity in rat. Biologia, 64(6): 1225-1231.
  • Jeyachandran, R., Mahesh, A., Cindrella, L., Sudhakar, S. and Pazhanichamy, K. (2009). Evaluation of antibacterial activity of plumbagin and the root extracts of Plumbago zeylanica L. Acta Biologica Cracoviensia Series Botanica, 51(1): 17–22.
  • Jeyachandran, R. and Mahesh, A. (2007). Agrobacterium rhizogenes mediated hairy root induction in Oxystelma esculentum (L.f). R. Br. Journal of Biological Research, 8: 207- 212.
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2007). DEN - induced cancer and its alleviation by Anisomeles malabarica (L.) R. Br. ethanolic leaf extract in male albino mice. International Journal of Cancer Research, 3(4): 174-179.
  • Mahesh, A. and Jeyachandran, R. (2005). Regeneration of Taraxacum officinale through nodal explants. J. Trop. Med. Plants, 6(2), 245-248.

BOOK CHAPTERS

  • Mahesh, A. and Thangadurai, D. Transformed hairy root induction: a tool for enhancement of secondary metabolites in Taraxacum officinale. In:  Thangadurai et al., (eds),  Molecular Agrobiology, (Accepted)
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2010). Glucosamine- a novel medicine for Arthritis. In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XXI, Ali Khan, I. and khanum, A (eds). Ukaaz publications, Hyderabad. 246-272
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2010). Epidemiology of Hot water epilepsy. In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XXI, Ali Khan, I. and khanum, A (eds). Ukaaz publications, Hyderabad. Pp 273-296
  • Mahesh, A., Jeyachandran, R., Cindrella, L. Thangadurai, D. and Pinheiro de Carvalho, M.A.A. (2008). Phytochemical, Pharmacological and Tissue Culture Studies on Taraxacum officinale Weber (Asteraceae).  In:  Biotechnology for food, Environment and Agriculture, Vol. I. Thangadurai, D. (eds.), Agrobios Press, India. pp. 235-251.
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Hepatoprotective Medicines, In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XIX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 114-142.
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Nephroprotective Plant Medcines, In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XIX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 143-168.
  • Jeyachandran, R., Mahesh, A., Krithika, G and Cindrella, L. (2008). Immunotoxicology, In: Role of Biotechnology in Medicinal and Aromatic, Vol- XX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 262-290.
  • Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Pathogenesis of Poliomyelitis. In: Herbal Medicine for Human Diseases, Vol- IV. Ali Khan, I. and khanum, A. (eds). Ukaaz publications, Hyderabad. pp 271-296.