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Dr. J. RAJENDHRAN

Assistant Professor
Department of Genetics
School of Biological Sciences
Madurai Kamaraj University
Madurai - 625 021, India
Tel :          0452-2456420
E mail: jrajendhran@gmail.com

 

HONOURS AND AWARDS

  • DBT- Rapid Grant for Young Investigator – 2010
  • DST Young Scientist – 2008
  • Young Scientist Award - Association of Microbiologists of India (AMI) – 2007.
  • Best Oral Presentation Award – Origene 2007, International Conference on Recent Trends in Biotechnology, Kalasalingam University, Krishnankoil, India. 5-6th January 2007.
  • SRF-2004 (Senior Research Fellowship by Council of Scientific and Industrial Research, New Delhi, India)
  • SLET-1999 (State Level Educational Test for lectureship, Bharathidasan University, Tiruchirapalli, India)
  • GATE -1998 (Graduate Aptitude Test in Engineering)
  • M. Phil academic prize – 1998 for proficiency in Research Methodology, The American College, Madurai, India. 
  • A. K. R. Thilagar prize – 1997 for proficiency in Immunology, The American College, Madurai, India. 

 

ONGOING RESEARCH PROJECTS

  • 2010-2013 Circulating Human Microbiome and Cardiovascular Diseases, Department of Biotechnology, India.
  • 2008-2011 Marine Metagenomics – Antimicrobial Drug Development from Marine and Estuarine Metagenome, Department of Science & Technology, India.

Ph.D STUDENTS

  • M. Pushpanathan – Antimicrobial Drug Development from Marine Metagenome – DBT JRF
  • Ms. A. Manjula  - Uncovering Cellulase Genes from Selected Metagenome –MKU-USRF
  • Mr. V. Dinakaran - Circulating Human Microbiome and Cardiovascular Diseases – DBT JRF

WORKSHOPS / WINTER SCHOOLS / SUMMER SCHOOLS CONDUCTED

  • Organizing Secretary, Winter School on Environmental Genomics, 27th Dec 2010 – 10th Jan 2011.
  • Convener, Summer School on PCR Applications, 17-31, March, 2010.
  • Convener, Summer School on Recombinant DNA Technology, 23-27 June, 2009.
  • Organizing Secretary, Winter School on Metagenomics, 2-16, March 2009.
  • Organizing Secretary, Winter School on Microbial Genome Typing, 10-24 December 2008.

MEMBERSHIP IN SCIENTIFIC SOCIETIES

  • Life Member – Association of Microbiologists of India (AMI)
  • Life Member – Biotechnology Research Society of India (BRSI)

PUBLICATIONS

  1. Manjula A, Sathyavathi S, Gunasekaran P and Rajendhran J (2011) Comparison of seven methods of DNA extraction from termitarium for functional metagenomic DNA library construction. Journal of Scientific and Industrial Research(Accepted)
  2. Jayashree S., Rajendhran J, Jayaraman K, Kalaichelvan G and Gunasekaran P (2011) Improvement of riboflavin production by Lactobacillus fermentum isolated from yoghurt. Food Biotechnology (Accepted).
  3. Rajendhran J. and Gunasekaran P. (2011) Microbial phylogeny and diversity: Small subunit ribosomal RNA sequence analysis and beyond. Microbiological Research. 166: 99-110
  4. Rajendhran J. and Gunasekaran P. (2010) Human Microbiomics. Indian Journal of Microbiology. 50: 109-112.
  5. Karuppanapandian T, Wang HW, Karuppudurai T, Rajendhran J, Kwon M, Jang CS, Kim S -H, Manoharan K and Kim W (2010) Efficiency of RAPD and ISSR markers in assessing genetic diversity and relationships in black gram (Vigna mungo L. Hepper) varieties. Canadian Journal of Plant Sciences90: 443-452.
  6. Rajendhran J. and Gunasekaran P. (2009) Human Genomics and Microbiomics: the post-genomics scenario. Current Science.  97: 140-141
  7. Senthilkumar V., Rajendhran J., Busby S.J.W. and Gunasekaran P (2009) Characterization of multiple promoters and transcript stability in the sacB­-sacC gene cluster in Zymomonas mobilis. Archives of Microbiology. 191: 529–541
  8. Rajendhran J. and Gunasekaran P. (2008) Strategies for accessing soil metagenome for desired applications. Biotechnology Advances. 26: 576-590. 
  9. Rajendhran J. and Gunasekaran P. (2007) Cloning, expression and characterization of penicillin G acylase from Bacillus badius. Journal of Bioscience and Bioengineering.103, 457-463.   
  10. Rajendhran J. and Gunasekaran P. (2007) Application of Cross-linked Enzyme Aggregates of Bacillus badius penicillin G acylase for the production of 6-aminopenicillanic acid. Letters in Applied Microbiology. 44, 43-49.       
  11.  Rajendhran J. and Gunasekaran P. (2004) Recent Biotechnological Interventions for Developing Improved Penicillin G Acylases. Journal of Bioscience and Bioengineering. 97, 1-13.          
  12. Rajendhran J., Krishnakumar V. and Gunasekaran P. (2003) Production of Penicillin G acylase from Bacillus sp.: Effect of medium components. World Journal of Microbiology and Biotechnology.19, 107-110.      
  13. Rajendhran J., Krishnakumar V. and Gunasekaran P. (2002) Optimization of a fermentation medium for the production of Penicillin G acylase from Bacillus sp. Letters in Applied Microbiology.35, 523-527.
  14. Rajendhran J. and Pandian RS. (2003) Microbial flora isolated from an urban population of non-bitting vector, Musca domestica and their susceptibility to antibiotics. Asian journal of Microbiology, Biotechnology and Environmental Science. 5, 101-105.
  15. Ramasamy S., Manoharan AC. and Rajendhran J. (2001) Antibacterial effect of various plant extracts on human pathogens. Indian Journal of Environment and Ecoplanning. 5, 317-319.
  16. Rajendhran J., Mani MA. and Navaneethakannan K. (1998) Antibacterial activity of some selected medicinal plants. Geobios. 25, 280-282.

BOOK CHAPTERS PUBLISHED

  1. Rajesh T, Rajendhran J and P. Gunasekaran (2011). Genomics Strategies for Environmental Bioremediation. Microbes in Environmental Management and Biotechnology. Springer Press. (Accepted)
  2. Rajesh T, Rajendhran J and Gunasekaran P (2011). Isolation of Metagenomic DNA and RNA from Soil: Microbial Diversity Analysis and Construction of Metagenomic Library.  Basic Protocols in Molecular Microbiology. (Accepted)
  3. Rajesh T, Anthony T, Rajendhran J and Gunasekaran P (2011). Alternate Expression Systems for High-level expression of Membrane Active Antibacterial Proteins. Advances in Bioprocesses in Food Industries, Volume IV. Asiatech Publishers. (In Press)
  4. Rajesh T, Rajendhran J, Pushpam P.L and Gunasekaran P (2011) Methods of Metagenomic DNA, RNA and Protein Isolation from Soil. In: Handbook of Molecular Microbial Ecology: Metagenomics in Different Habitats. John Wiley & Sons, NY, USA (In Press)
  5. Geetha K., Rajnish K. N. Rajendhran J. and Gunasekaran P. (2008) Synthesis of bacterial polysaccharides as a limiting factor for biofuel production. In: Microbial Polysaccharides (Ed: Ullrich M) Horizon Scientific Press, Norwich, UK.

PRESENTATIONS IN INTERNATIONAL CONFERENCES

  1. Dinakaran V, Rathinavel A. Gunasekaran P and Rajendhran J. Detection and characterization of bacteremia in rheumatic heart disease patients. International Conference on Genomics Sciences, VII Convention of Biotech Research Society, India, Indo-Italian Workshop on Industrial and Pharmaceutical Biotechnology, Madurai Kamaraj University, Madurai, India 12-14th, November, 2010
  2. Manjula A, Rajendhran J and Gunasekaran P. Comparison of seven methods of DNA extraction from termitarium for functional metagenomic DNA library construction. International Conference on Genomics Sciences, VII Convention of Biotech Research Society, India, Indo-Italian Workshop on Industrial and Pharmaceutical Biotechnology, Madurai Kamaraj University, Madurai, India 12-14th, November, 2010
  3. Pushpanathan M, Rajendhran J and Gunasekaran P. Identification and characterization of a novel gene coding for alkaline protease from metagenome of marine environment. International Conference on Genomics Sciences, VII Convention of Biotech Research Society, India, Indo-Italian Workshop on Industrial and Pharmaceutical Biotechnology, Madurai Kamaraj University, Madurai, India 12-14th, November, 2010
  4. Rajendhran J. and Gunasekaran P. Improved production of Bacillus badius penicillin G acylase in Escherichia coli by the coexpression of tRNA genes. International Conference on New Horizons in Biotechnology & 4th convention of BRSI, Trivandrum, India. 26-29th November 2007.
  5. Rajendhran J. and Gunasekaran P. Strategies for the improved production of bacillus badius penicillin G acylase. Origene 2007, International Conference on Recent Trends in Biotechnology, Kalasalingam University, Krishnan Kovil, India. 5-6th January 2007 (Conferred Best Oral Presentation Award).
  6. Rajendhran J. and Gunasekaran P. Independent expression of Bacillus badius penicillin acylase subunits improves the expression in Escherichia coli.3rd convention of BRSI & International Conference on exploring horizons in Biotechnology - a Global venture, Sardar Patel University, Vallabh Vidyanagar, India. 2-4th November 2006. 
  7. Rajendhran J. and Gunasekaran P. Cloning and partial sequencing of pac gene of Bacillus sp. International Conference on Interface of Chemistry and Biology, Regional Research Laboratory, Trivandrum, India. 28-30th April 2003.
  8. Gunasekaran P. and Rajendhran J. Biochemical engineering of bacterial penicillin acylases. International Conference on Interface of Chemistry and Biology, Regional Research Laboratory, Trivandrum, India.28-30th April 2003.
  9. Rajendhran J. and Pandian RS. Vector potential of Musca domestica in an urban area. Fourth International Symposium on Vectors and Vector borne Diseases. Defense Research and Development Establishment, Gwalior, India. 18-20th February 1999.

PRESENTATIONS IN NATIONAL CONFERENCES

  1. Vignesh S.P., Aparna S. Pushpanathan M, Rajendhran J. and Gunasekaran P. Cloning of novel hydrolases from marine metagenome. Aqua-Terr Annual Symposium. Madurai Kamaraj University, Madurai. 10th March 2010.
  2. Pushpanathan M, Rajendhran J. and Gunasekaran P. Extracellular production of Alcaligenes faecalis penicillin G acylase in Escherichia coli and its one-step purification. 50th Annual Conference of the Association of Microbiologists of India. National Chemical Laboratory, Pune, Dec 15 to 18, 2009.
  3. Rajendhran J. Metagenomics and its environmental applications. National Seminar on “Current Advances in Applied Genetics & Bioethics”, Nirmala College for Women, Coimbatore, Sep 18th & 19th, 2009.
  4. Rajendhran J. Development of recombinant penicillin acylase for 6-aminopenicillanic acid production. 48th Annual Conference of Association of Microbiologists of India, Indian Institute of Technology, Bhopal, India. 18-21, December 2007 (AMI-Young Scientist Award Lecture).
  5. Prabhu P., Rajendhran J. and Gunasekaran P. Cloning and overexpression of penicillin G acylase (pac) gene of Thermus thermophilus in Escherichia coli. Aqua-Terr Annual Symposium. Madurai Kamaraj University, Madurai. 10th March 2007.
  6. Divya R., Rajendhran J. and Gunasekaran P. Expression of Bacillus badius pac gene in Bacillus megaterium for the production of extracellular penicillin G Acylase.Aqua-Terr Annual Symposium. Madurai Kamaraj University, Madurai. 10th March 2007.
  7. Rajendhran J. and Gunasekaran P. Extracellular production of Bacillus badius penicillin G acylase using Pichia pastoris expression system. 47th Annual Conference of Association of Microbiologists of India, Barkatullah University, Bhopal, India. 6-8 December 2006.
  8. Rajendhran J. and Gunasekaran P. Molecular cloning and characterization of gene coding for penicillin G acylase from Bacillus badius. First conference of Biotechnology Research Society of India, North Maharastra University, Jalgaon, India. 25-27th November 2004.
  9. Rajendhran J., Krishnakumar V. and Gunasekaran P. Application of immobilized cells of Bacillus sp. for the production of 6-aminopenicillanic acid. 43rd Annual Conference of Association of Microbiologists of India, CCS Haryana agricultural University, Hisar, India. 11-13th December 2002.
  10. Rajendhran J. and Pandian RS. Occurrence of spatial variation in the pathogens isolated from the houseflies. Symposium on Vectors and Vector borne diseases, The American College, Madurai, India. 29-30th January 1999.  
  11. Rajendhran J. and Pandian RS. Determination of antimicrobial effectiveness of antibiotics against bacterial pathogens isolated from urban houseflies. 39th Annual Conference of Association of Microbiologists of India, Mangalore, India. 5-6th December 1998.
  12. Pandian RS. and Rajendhran J. Occurrence of Biodiversity among microbial pathogens isolated from urban houseflies. 39th Annual Conference of Association of Microbiologists of India, Mangalore, India. 5-6th December 1998.
  13. Rajendhran J. and Pandian RS. Rhythm in the foraging behaviour of Musca domestica nebulo (FABR.). Third Symposium on Vectors and Vector borne Diseases. Puri, India. 30th May-1st June 1998.    
  14. Rajendhran J. and Pandian RS. Isolation of bacterial pathogens from the proboscis of Musca domestica. Third Symposium on Vectors and Vector borne Diseases. Puri, India. 30th May-1st June 1998.
  15. Rajendhran J. and Navaneethakannan K. Antibacterial activity of some selected medicinal plants. Aqua-Terr Annual Symposium. Madurai Kamaraj University, Madurai. 27-28th February 1998.

RESEARCH INTEREST

  • Human Microbiomics and Cardiovascular Diseases
  • Role microbiome in the development of immune system
  • Marine Metagenomics for novel drug discovery
  • Mobile Metagenomics and Environmental Genomics
  • Genomic diversity of bacterial pathogens and host interaction